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Associate Professor of Human Genetics and Biostatistics
Director, Array Data Analysis Group
David Geffen School of Medicine at UCLA
Dr. Horvath is an Assistant Professor in Human Genetics and
Biostatistics at UCLA.
His expertise lies in bioinformatics and statistical genetics. He directs the
Array Data Analysis Group
at UCLA. His research interests include: a) allelic association tests for mapping
complex disease genes based on genetic markers, b) data mining methods
for DNA and tissue microarray data. He has published extensively on
allelic association tests, e.g., he has worked on family-based allelic
association tests that do not require parental information but instead
use sibling controls. He has developed the sibship disequilibrium test
(SDT) and is one of the authors of the widely used software package
FBAT.
Lately, he has extended these methods to haplotype data.
Steve Horvath's research in data mining methods focuses on supervised
and unsupervised methods for analyzing array data. Lately, he is
investigating methods that are at the intersection of genetic marker and
gene expression data, e.g., he has studied family-based tests for
correlation between gene expression and trait values and is working on
adapting random forest predictors to SNP and microarray data.
Further he develops methods for constructing and validating gene
co-expression networks.
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