Genetics Links
- UCLA Homepage -
Here you can find information on the University. Examples: Admissions and Services, Academic Programs, Campus Directions and the UCLA Bookstore
- Genome Centers -
construction of high resolution Radiation Hybrid maps of the
human genome and the sequencing of large, contiguous genomic
regions. Examples Centers: Stanford Human Genome Center, Michigan
Human Genome Center and National Center for Genome Resources.
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Linkage Mapping -
A list of statistical methods used for genetic mapping. Examples: CHLC homepage, The Genome Database USA (GDB) and The Genetic Location Database (LBD).
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Physical Mapping -
A compiled list of Physical mapping can be found here. Examples: Chromosome 9, Yac - orders and PI, PAC, BAC -orders.
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Protein Analysis -
A list of Software for the Analysis of Genes and Proteins. Examples: MOTIF, Protein Structure Predictions and GCG Homepage.
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Protein Prediction -
Web-based tools for the use of predicting proteins from genetic sequences.
- PSI-BLAST -
Detects distant protein homologs using an iterative search method. The web form does not allow you to search against ESTs or nucleotide sequences. Alternative database search methods: BLAST, FASTA
- InterPro -
Detects domains in a protein sequence, and very distant homologs. Similar tools: SMART, PIMA, CD-search.
- ClustalW -
Performs multiple sequence alignment. If you select the "gcg MSF" option under "OUTPUT FORMAT", you can cut and paste the alignment into BOXSHADE to produce nice pictures with a color scheme for conserved residues. Alternatives: T-COFFEE (download), Dialign, Multalin
- SignalP -
Detects secretory signal peptides in protein sequences. Perhaps more accurate than PSORT. Nice graphical output
- PSORT -
Detects secretory signal peptides in protein sequences. Predicts transmembrane helices. Various other predictions (some of them extremely inaccurate).
- TMHMM -
Predicts transmembrane helices in protein sequences. Nice graphical output.
- PHD -
Predicts protein transmembrane helices and secondary structure. One of the most accurate prediction methods, but the website and output are extremely user-unfriendly. The website bundles PHD with a number of other prediction programs. Alternative programs to predict transmembrane helices: DAS, SOSUI, TMpred. An alternative program to predict protein secondary structure: Jpred
- RasMol -
Interactive visualization of 3D molecular structures
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Sequence Analysis -
Single sequence alignments, Multiple sequence alignments, and Secondary structure prediction. Examples: Sequence Homology Searches, EST's, Gene Prediction from Genomic Sequence, Useful Sequence related Webpages and Large Scale Sequencing Related Genome Centers.
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SNP Databases -
Searchable SNP databases from around the internet. Examples include NCBI dbSNP and Gene Canvas.
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A User's Guide to the Human Genome -
published by Nature Genetics
