1. Wang SS, Shi W, Wang X, Velky L, Greenlee S, Wang MT, Drake TA, Lusis AJ. Mapping, genetic isolation, and characterization of genetic loci that determine resistance to atherosclerosis in C3H mice. Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2671-6. Epub 2007 Oct 4.
  2. Lusis AJ, Yu J, Wang SS. The problem of passenger genes in transgenic mice.Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2100-3. Epub 2007 Aug 9.
  3. Lee JC, Weissglas-Volkov D, Kyttälä M, Sinsheimer JS, Jokiaho A, de Bruin TW, Lusis AJ, Brennan ML, van Greevenbroek MM, van der Kallen CJ, Hazen SL, Pajukanta P. USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2222-7. Epub 2007 Aug 2.
  4. Fuller TF, Ghazalpour A, Aten JE, Drake TA, Lusis AJ, Horvath S. Weighted gene coexpression network analysis strategies applied to mouse weight Mamm Genome. 2007 Jul;18(6-7):463-72. Epub 2007 Aug 1.
  5. Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol. 2007 Jul 26;8(7):R149
  6. Wang SS, Schadt EE, Wang H, Wang X, Ingram-Drake L, Shi W, Drake TA, Lusis AJ. Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data. Circ Res. 2007 Aug 3;101(3):e11-30. Epub 2007 Jul 19
  7. Moen CJ, Tholens AP, Voshol PJ, de Haan W, Havekes LM, Gargalovic P, Lusis AJ, van Dyk KW, Frants RR, Hofker MH, Rensen PC. The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides.J Lipid Res. 2007 Oct;48(10):2182-92. Epub 2007 Jul 3.
  8. Davis RC, Jin A, Rosales M, Yu S, Xia X, Ranola K, Schadt EE, Lusis AJ. A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background Genomics. 2007 Sep;90(3):306-13. Epub 2007 Jun 27
  9. Orozco LD, Kapturczak MH, Barajas B, Wang X, Weinstein MM, Wong J, Deshane J, Bolisetty S, Shaposhnik Z, Shih DM, Agarwal A, Lusis AJ, Araujo JA. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.Circ Res. 2007 Jun 22;100(12):1703-11. Epub 2007 May 10
  10. Gharavi NM, Gargalovic PS, Chang I, Araujo JA, Clark MJ, Szeto WL, Watson AD, Lusis AJ, Berliner JA. High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1346-53. Epub 2007 Mar 22
  11. Shih DM, Xia YR, Wang XP, Wang SS, Bourquard N, Fogelman AM, Lusis AJ, Reddy ST. Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice.Circ Res. 2007 Apr 27;100(8):1200-7. Epub 2007 Mar 22
  12. Meng H, Vera I, Che N, Wang X, Wang SS, Ingram-Drake L, Schadt EE, Drake TA, Lusis AJ. Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics.Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4530-5. Epub 2007 Mar 6.
  13. Itoh Y, Melamed E, Yang X, Kampf K, Wang S, Yehya N, Van Nas A, Replogle K, Band MR, Clayton DF, Schadt EE, Lusis AJ, Arnold AP. Dosage compensation is less effective in birds than in mammals.J Biol. 2007;6(1):2.
  14. Feng X, Li H, Rumbin AA, Wang X, La Cava A, Brechtelsbauer K, Castellani LW, Witztum JL, Lusis AJ, Tsao BP. ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia J Lipid Res. 2007 Apr;48(4):794-805. Epub 2007 Jan 26
  15. Shaposhnik Z, Wang X, Weinstein M, Bennett BJ, Lusis AJ. Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):621-7. Epub 2006 Dec 7.
  16. Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L852-60. Epub 2006 Nov 22.
  17. Parks BW, Lusis AJ, Kabarowski JH. Loss of the lysophosphatidylcholine effector, G2A, ameliorates aortic atherosclerosis in low-density lipoprotein receptor knockout mice Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2703-9. Epub 2006 Sep 21.
  18. Brouwers MC, Cantor RM, Kono N, Yoon JL, van der Kallen CJ, Bilderbeek-Beckers MA, van Greevenbroek MM, Lusis AJ, de Bruin TW. Heritability and genetic loci of fatty liver in familial combined hyperlipidemia.J Lipid Res. 2006 Dec;47(12):2799-807. Epub 2006 Sep 13.
  19. Ghazalpour A, Doss S, Zhang B, Wang S, Plaisier C, Castellanos R, Brozell A, Schadt EE, Drake TA, Lusis AJ, Horvath S. Integrating genetic and network analysis to characterize genes related to mouse weight PLoS Genet. 2006 Aug 18;2(8):e130. Epub 2006 Jul 5.
  20. Gargalovic PS, Gharavi NM, Clark MJ, Pagnon J, Yang WP, He A, Truong A, Baruch-Oren T, Berliner JA, Kirchgessner TG, Lusis AJ. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells.Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):2490-6. Epub 2006 Aug 24
  21. Lusis AJ. A thematic review series: systems biology approaches to metabolic and cardiovascular disorders.J Lipid Res. 2006 Sep;47(9):1887-90
  22. Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, Navab M, Fogelman AM, Lusis AJ, Young S, Reddy ST. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2.J Biol Chem. 2006 Oct 6;281(40):29491-500. Epub 2006 Aug 4
  23. Estrada-Smith D, Collins AR, Wang X, Crockett C, Castellani L, Lusis AJ, Davis RC. Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice.Diabetes. 2006 Aug;55(8):2265-71.
  24. Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, Drake TA, Lusis AJ. Tissue-specific expression and regulation of sexually dimorphic genes in mice Genome Res. 2006 Aug;16(8):995-1004. Epub 2006 Jul 6
  25. Zhang Y, Wang X, Vales C, Lee FY, Lee H, Lusis AJ, Edwards PA. FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2316-21. Epub 2006 Jul 6.
  26. Bhasin KK, Yu JM, Tward A, Shih D, Campbell DA, Lusis AJ. Trypanosoma congolense: paraoxonase 1 prolongs survival of infected mice. Exp Parasitol. 2006 Nov;114(3):240-5. Epub 2006 May 8
  27. Castellani LW, Chang JJ, Wang X, Lusis AJ, Reynolds WF.Transgenic mice express human MPO -463G/A alleles at atherosclerotic lesions, developing hyperlipidemia and obesity in -463G males. J Lipid Res. 2006 Jul;47(7):1366-77. Epub 2006 Apr 25
  28. Lum PY, Chen Y, Zhu J, Lamb J, Melmed S, Wang S, Drake TA, Lusis AJ, Schadt EE. Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.J Neurochem. 2006 Apr;97 Suppl 1:50-62.
  29. Ghazalpour A, Wang X, Lusis AJ, Mehrabian M. Complex inheritance of the 5-lipoxygenase locus influencing atherosclerosis in mice. Genetics. 2006 Jun;173(2):943-51. Epub 2006 Apr 19.
  30. Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene. 2006 Jun 15;25(25):3528-36. Epub 2006 Apr 10.
  31. Su Z, Li Y, James JC, Matsumoto AH, Helm GA, Lusis AJ, Shi W. Genetic linkage of hyperglycemia, body weight and serum amyloid-P in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice. um Mol Genet. 2006 May 15;15(10):1650-8. Epub 2006 Apr 4.
  32. Miyoshi T, Li Y, Shih DM, Wang X, Laubach VE, Matsumoto AH, Helm GA, Lusis AJ, Shi W. Deficiency of inducible NO synthase reduces advanced but not early atherosclerosis in apolipoprotein E-deficient mice Life Sci. 2006 Jul 4;79(6):525-31. Epub 2006 Mar 3.
  33. Wang S, Yehya N, Schadt EE, Wang H, Drake TA, Lusis AJ. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity PLoS Genet. 2006 Feb;2(2):e15. Epub 2006 Feb 3.
  34. Shih DM, Kast-Woelbern HR, Wong J, Xia YR, Edwards PA, Lusis AJ. A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids J Lipid Res. 2006 Feb;47(2):384-92. Epub 2005 Nov 3.
  35. Ozer EA, Pezzulo A, Shih DM, Chun C, Furlong C, Lusis AJ, Greenberg EP, Zabner J. Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing FEMS Microbiol Lett. 2005 Dec 1;253(1):29-37. Epub 2005 Oct 5.
  36. Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nat Genet. 2005 Nov;37(11):1224-33. Epub 2005 Oct 2. Erratum in: Nat Genet. 2005 Dec;37(12):1381.
  37. Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellini LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE. Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels Genomics. 2005 Nov;86(5):505-17. Epub 2005 Aug 29.
  38. Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AD, Lusis AJ, Costa LG. Role of paraoxonase (PON1) status in pesticide sensitivity: genetic and temporal determinants.Neurotoxicology. 2005 Aug;26(4):651-9
  39. Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background Genomics. 2005 Sep;86(3):259-70.
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  42. Bodnar,JS, Chatterjee,A, Castellani,LW, Ross,DA, Ohmen,J, Cavalcoli,J, Wu,C, Dains,KM, Catanese,J, Chu,M, Sheth,SS, Charugundla,K, Demant,P, West,DB, de Jong,P, Lusis,AJ: Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat.Genet. 30:110-116, 2002
  43. Brennan,ML, Anderson,MM, Shih,DM, Qu,XD, Wang,X, Mehta,AC, Lim,LL, Shi,W, Hazen,SL, Jacob,JS, Crowley,JR, Heinecke,JW, Lusis,AJ: Increased atherosclerosis in myeloperoxidase-deficient mice. J.Clin.Invest 107:419-430, 2001
  44. Lusis, A. J., Fogelman, A. M., and Fonarow, G. C. Genetic basis of atherosclerosis: Part I, New genes and pathways. Circulation . 2004.
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  46. Liu,D, Singh,RP, Khan,AH, Lusis,AJ, Davis,RC, Smith,DJ: Mapping behavioral traits by use of genome-tagged mice. Am.J.Geriatr.Psychiatry 12:158-165, 2004
  47. Liu,D, Singh,RP, Khan,AH, Bhavsar,K, Lusis,AJ, Davis,RC, Smith,DJ: Identifying loci for behavioral traits using genome-tagged mice. J.Neurosci.Res. 74:562-569, 2003
  48. Wang,X, Gargalovic,P, Wong,J, Gu,JL, Wu,X, Qi,H, Wen,P, Xi,L, Tan,B, Gogliotti,R, Castellani,LW, Chatterjee,A, Lusis,AJ: Hyplip2, a New Gene for Combined Hyperlipidemia and Increased Atherosclerosis. Arterioscler.Thromb.Vasc.Biol. 2004
  49. Ghazalpour,A, Doss,S, Yang,X, Aten,J, Toomey,EM, Van Nas,A, Wang,S, Drake,TA, Lusis,AJ: Thematic review series: The Pathogenesis of Atherosclerosis. Toward a biological network for atherosclerosis. J.Lipid Res. 45:1793-1805, 2004

    50.   Krass,KL, Colinayo,V, Ghazalpour,A, Vinters,HV, Lusis,AJ, Drake,TA: Genetic loci contributing to age-related hippocampal lesions in mice. Neurobiol.Dis. 13:102-108, 2003

  50. Brown,MD, Jin,L, Jien,ML, Matsumoto,AH, Helm,GA, Lusis,AJ, Frank,JS, Shi,W: Lipid retention in the arterial wall of two mouse strains with different atherosclerosis susceptibility. J.Lipid Res. 45:1155-1161, 2004
  51. Mar,R, Pajukanta,P, Allayee,H, Groenendijk,M, Dallinga-Thie,G, Krauss,RM, Sinsheimer,JS, Cantor,RM, de Bruin,TW, Lusis,AJ: Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ.Res. 94:993-999, 2004
  52. MacLellan,WR, Lusis,AJ: Dilated cardiomyopathy: learning to live with yourself. Nat.Med. 9:1455-1456, 2003
  53. Lusis,AJ: Atherosclerosis. Nature 407:233-241, 2000
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  55. Shi,W, Brown,MD, Wang,X, Wong,J, Kallmes,DF, Matsumoto,AH, Helm,GA, Drake,TA, Lusis,AJ: Genetic backgrounds but not sizes of atherosclerotic lesions determine medial destruction in the aortic root of apolipoprotein E-deficient mice. Arterioscler.Thromb.Vasc.Biol. 23:1901-1906, 2003
  56. Lusis,AJ: Genetic factors in cardiovascular disease. 10 questions. Trends Cardiovasc.Med. 13:309-316, 2003
  57. Welch,CL, Bretschger,S, Wen,PZ, Mehrabian,M, Latib,N, Fruchart-Najib,J, Fruchart,JC, Myrick,C, Lusis,AJ: Novel QTLs for HDL levels identified in mice by controlling for Apoa2 allelic effects: confirmation of a chromosome 6 locus in a congenic strain. Physiol Genomics 17:48-59, 2004
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