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1. Fan, G., and Katz, D.M. (1993) Non-neuronal cells inhibit the catecholaminergic differentiation of primary sensory neurons: role of leukemia inhibitory factor. Development 118: 83-93.
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2. Hertzberg, T., Fan, G., Finley, J.C.W., Erickson, J.T., and Katz, D.M. (1994) BDNF supports mammalian chemoafferent neurons in vitro and following peripheral target removal in vivo. Dev. Biol. 166: 801-11.
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3.
Kucera, J., Fan, G., Jaenisch, R., Linnarsson, S., and Ernfors, P. (1995) Dependence of developing group Ia afferents on neurotrophin-3. J. Comp. Neurol. 363: 307-320.
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4. Kucera, J., Fan, G., Walro, J., Copray, S., Tessarollo, L., and Jaenisch, R. (1998) Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles. Neuroreport9: 905-909.
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5. Fan, G., Jaenisch, R., and Kucera, J. (1999) A role for p75 receptor in NT3 functioning during the development of limb proprioception. Neuroscience 90: 259-268.
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6. Bates, B., Rios, M., Trumpp, A., Chen, C., Fan, G., Bishop, J.M., and Jaenisch, R. (1999) Neurotrophin-3 is required for proper cerebellar development. Nature Neurosci. 2: 115-7 .
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7. Fan, G., Copray, S., Wong, E., Yan, Q., Jones, K., Walro, J., Jaenisch, R., and Kucera, J. (2000) Formation of the cranial proprioceptive system requires multiple neurotrophins. Developmental Dynamics 218: 359-370.
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8. Endres, M, Fan, G (equal contribution), Hirt, L., Fujji, M., Liu, X., Jaenisch, R., and Moskowitz, M.A. (2000) Ischemic brain damage after selectively modifying BDNF or NT-4 expression in vivo. J. Cereb.Blood Flow. Metab. 20: 139-144.
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9. Fan, G., Lei, X. , Cheng, H., Wang, X., Sun, B., and Hu, G. (2000) Targeted disruption of NDST-1 gene leads to pulmonary hypoplasia and neonatal respiratory distress in mice. FEBS. Letter 467: 7-11.
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10. Fan, G., Egles, C., Sun, Y., Minichiello, L., Renger, J., Klein, R., Liu, G., and Jaenisch, R. (2000) Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature Neuroscience 3: 350-357.
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11. Endres, M., Fan, G., Meisel, A., Dirnagl, U.and Jaenisch, R. 2001. (2001) Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in postmitotic neurons. Neuroreport 12: 3763-66.
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12. Fan, G., Beard, C., Chen, R., Csankovszki, G., Sun, Y., Siniaia, M., Bates, B., Lee, P., Trumpp, A., Poon, C., Wilson, C., and Jaenisch, R. (2001) DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals. Journal of Neuroscience 21: 788-797.
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13. Sun, Y., Nadal-Vicens, M., Misono, S., Lin, MZ., Zubiaga, A., Hua, X., Fan, G., Greenberg, ME. (2001) Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104: 365-376.
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14. Fan, G., Siniaia, M., Poon, C., and Jaenisch, R. (2001) Effect of DNA hypomethylation on neural control of respiration: a genetic model. Adv. Exp. Med. Biol. 499: 195-200.
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15. Akbarian, S., Bates, B., Liu, RJ., Skirball, SL., Pejchal, T., Coppola, V., Sun, LD., Fan, G., Kucera, J., Wilson, MA., Tessarollo, L., Kosofsky, BE., Taylor, JR., Bothwell, M., Nestler, EJ., Aghajania, GK., and Jaenisch, R. (2001) Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawl. Molecular Psychiatry 6: 593-604.
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16. Rio, M., Fan, G., Fekete, C., Kelly, J., Bates, B., Lechan, RM., Jaenisch, J. (2001) Conditional deletion of brain-drived neurotrophic factor in the postnatal brain causes hyperactivity and obesity. Molecular Endocrinology. 15: 1748-1757.
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17. Ge, W., Martinowich, K., Wu, X., He, F., Miyamoto, A., Fan, G., Weinmaster, G., and Sun, YE. (2002) Notch signaling promotes astrogliogenesis via direct CSL mediated glial gene activation. Journal of Neuroscience Research 69: 848-860.
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18. Endres, M., Fan, G., Hirt, L. and Jaenisch, R. (2003) Stroke damage in mice after knocking the NT4 gene into the BDNF locus. J. Cereb.Blood Flow. Metab. 23: 150-153.
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19. Martinowich, K., Hatorri, D., Wu, H., Fouse, S., He, F., Hu, Y., Fan, G*., Sun, Y*. (*Corresponding authors) (2003) DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 302: 890-893.
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20. Chi, M.M., Fan, G., Fox, E.A. (2004) Increased short-term food satiation and sensitivity to cholecystokinin in neurotrophin-4 knock-in mice. Am J Physiol Regul Integr Comp Physiol. 2004 Nov;287(5):R1044-53.
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21. Feng, J., Chang, H., Li, E., and Fan. G. (2005) Dynamic expression of De novo DNA methyltransferases Dnmt3a and 3b in the central nervous system. Journal of Neuroscience Research. 79, 734-746.
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22. Lyckman, AW., Fan, G., Rios, M., Jaenisch, R., Sur, M. (2005) Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor. Visual Science 22, 27-36.
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23. He, F., Ge, W., Zhu, W., Becker-Catania, S., Martinowich, K., Wu, H., Coskun, V., Fan, G., deVellis, J., Sun, Y. (2005) A positive autoregulation loop of JAK-STAT signaling is part of the clock mechanism regulating astrogliogenesis. Nature Neuroscience. 8, 616-625.
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24. Fan, G. and Hutnick, L. (2005) Methyl-CpG binding proteins in the nervous system (review paper). Cell Research 4, 255-61.
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25. Fan, G., Martinowich, K., Chin, M., He, F., Fouse, S., Hutnick, L., Hattori, D., Ge, W., Shen, Y., Wu, H., ten Hoeve, T., Shuai, K., and Sun, Y. (2005) DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 2005 Aug;132(15):3345-56.
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26. Shen, Y., Chow, J., Wang, Z., Fan, G. (2006). Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Human Molecular Genetics 2006 15(17):2623-35.
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27. Lu Y-C., Song J., Cho H-Y, Fan G., Yokoyama K.K., and Chiu R. (2006).
Cyclophilin A protects Peg3 from hypermethylation and inactive histone modification
J. Biol. Chem. 2006 281:39081-7. Epub 2006 Oct 26.
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28. Golshani, P., Hutnick, L., Schweizer, F., Fan, G. (2007). Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus and Related System doi: 10.1017/S1472928807000222, Published online by Cambridge University Press 05 Mar 2007
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29. Feng, J., Fouse, S., Fan, G. (2007). Epigenetic regulation of neural gene expression and neuronal function. Pediatric Research 2007 May;61(5 Pt 2):58R-63R
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30. Coskun, V., Wu, H., Blanchi, B., Tsao, S., Kim, K., Zhao, J., Biancotti, J-C., Hutnick, L., Krueger, RC., Fan, G., de Vellis, J., Sun, YE. (2008). Multipotent CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. PNAS 2008 105(3):1026-31.
31. Fouse, S., Shen, Y., Pellegrini, M., Cole, S., Meissner, A., Van Neste, L., Jaenisch, R., Fan, G. (2008). Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, Polycomb binding and histone H3 lys4/lys27 trimethylation. Cell Stem Cell 2008 2(2):160-9
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32. Shen, Y., Matsuno, Y., Fouse, S., Rao, N., Root, S., Xu, R.H., Pellegrini, Riggs, A., Fan, G. (2008). X-inactivation in female human embryonic stem cells is in a non-random pattern and prone to epigenetic alterations. PNAS 2008 published online March 13, 2008, 10.1073/pnas.0712018105.
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